Share Tweet Could this bacterium cause Parkinson’s disease?The bacteria responsible for stomach ulcers have been linked to Parkinson’s disease, according to researchers in the US. Mice infected with Helicobacter pylori went onto develop Parkinson’s like symptoms.The study, presented at a meeting of the American Society for Microbiology, argues that infection could play “a significant role”.The charity Parkinson’s UK said the results should be treated with caution.Parkinson’s disease affects the brain and results in slow movements and a tremor.Middle-aged mice, the equivalent of being between 55 and 65 in humans, were infected. Six months later they showed symptoms related to Parkinson’s, such as reduced movement and decreased levels of a chemical, dopamine, in the brain.These changes were not noticed in younger mice.ToxicDr Traci Testerman, from the Louisiana State University Health Sciences Center, said: “Our findings suggest that H. pylori infection could play a significant role in the development of Parkinson’s disease in humans.“The results were far more dramatic in aged mice than in young mice, demonstrating that normal ageing increases susceptibility to Parkinsonian changes in mice, as is seen in humans.”The researchers believe the bacteria are producing chemicals which are toxic to the brain.They said H. pylori was able to “steal” cholesterol from the body and process it by adding a sugar group.Dr Testerman said this new chemical was almost identical to one found in seeds from the cycad plant, which had been shown to trigger a Parkinson’s-like disease among people in Guam.She told the BBC: “H. pylori eradication in late stage Parkinson’s disease is unlikely to result in significant improvement.“Certain neurons are killed before symptoms begin, and more are killed as the disease progresses. Those neurons will not grow back.”Dr Kieran Breen, director of research at Parkinson’s UK, said: “We believe Parkinson’s is most likely caused by a combination of environmental factors together with an individual’s genetic susceptibility to developing the condition.He said there was some evidence that bacteria can prevent the main drug to treat Parkinson’s, levodopa, being absorbed, but there was no strong evidence that people who have H. pylori in their gut are actually more likely to develop Parkinson’s.He added: “The current study is interesting and suggests that the bacteria may release a toxin that could kill nerve cells.“However, the results should be treated with caution. The research was carried out in mice that were infected with relatively high doses of the bacterium or its extract.“While they developed movement problems, we don’t know whether this was actually due to the death of nerve cells. Further research needs to be carried out”.BBC News HealthLifestyle Bacteria ‘linked’ to Parkinson’s disease by: – May 23, 2011 20 Views no discussions Sharing is caring! Share Share
RelatedPosts CAF gives date for resumption of AFCON 2021, Qatar 2022 qualifiers CAF, NFF honour Kanu at 44 CAF postpones Africa Cup of Nations, unveils new format for CL, CC The Africa Cup of Nations 2021 will not be postponed amid the coronavirus outbreak, the Confederation of African Football has confirmed. Football activities worldwide have been on hold as a result of the global pandemic, which has taken nearly 20,000 lives to date. Recently, Caf announced the postponement of the 2020 African Nations Championship indefinitely, after hosts Cameroon had requested the rescheduling of the biennial tournament. However, this is not the case for Afcon 2021 – also to take place in the Central African country – after the continent’s football governing body confirmed the dates will remain unchanged unless the situation changes. Acting general secretary Abdelmounaim Bah believes the qualifiers can still be completed within the remaining international windows for 2020, thus, there is no basis for a postponement at this stage. “For now, the Africa Cup of Nations is still scheduled for January to February 2021,” Bah told Goal. “The only reason we would shift Afcon would be a situation [Covid-19] that continues into the year 2020 and if this current crisis does not allow us to play all the qualification matches. “We still have four qualifying days to play and we can play them in two international windows. “We have four at our disposal: June, September, October, November. At this point, anything is possible. “If we can’t play matchdays three and four in June, we will play them otherwise in September or October and we will play matchdays five and six in November.” Afcon 2021 is the 33rd edition of the event, and is scheduled to take place from January 9 to February 6, 2021 in Cameroon.Tags: Abdelmounaim BahAfrica Cup of NationsAfrican Nations ChampionshipConfederation of African Football
Indian batting legend VVS Laxman said Shikhar Dhawan should open the Indian innings along with Rohit Sharma in the forthcoming ICCChampions Trophy in England.The Indian selectors are yet tofinalise the squad for the tournament, of which India are the defendingchamps, but Laxman, speaking exclusively to India Today, said Dhawanshould be on the flight to London next month.Playing for theSunrisers Hyderabad, Dhawan made a 50-ball 70 against Delhi Daredevils a couple of days ago. Laxman, being a mentor of the team, says thesouthpaw seems ready for the India duty again.”Shikhar has beenbatting really well from the first match. Unfortunately, he has not been able to convert that into a big score but in last match he did reallywell and got a very good half century against Delhi. He’s batting well,he’s timing well, has made some technical changes in his batting andalso looks in a great space as far as his mind is concerned,” saidLaxman.The 31-year-old from Delhi was dropped midway throughthe ODI series against England earlier this year after making just 12runs in two matches. However, with KL Rahul set to miss the tournamentdue to an injury, Laxman asserts that Dhawan would be an idealreplacement.”I feel that Shikhar should open along with RohitSharma. If you remember, he had a big role to play in the last Champions Trophy win as well. This combination of Dhawan and Rahul is alwayslethal and puts the bowlers under tremendous pressure. So, I believeselectors will be watching him closely and I feel that, the kind ofrhythm he is in, he’s giving a lot of confidence to a lot of people. We, as a franchise, are also very pleased with the way Shikhar has beencontributing to the Sunrisers’ success so far.”advertisementDhawan wasadjudged the player of the Series in the last edition of the ChampionsTrophy, scoring 363 runs from five games, including two centuries.Not just Dhawan, ‘Very Very Special’ Laxman is also quite impressed withthe work ethics shown by Yuvraj Singh, another Hyderabad IPL teamplayer.”Yeah, Yuvraj’s return at the international level hasbeen a brilliant one. If you see, he performed really well in thedomestic cricket, got a double hundred and earned his recall. Then camethat phenomenal knock against England in Cuttack where he got a 150. The good thing about him is that he is not only thinking about doing wellfor Hyderabad in the IPL but also looking ahead.”I am veryimpressed with his work ethics, the amount of time he is spending on his fitness, working on his fielding and also focusing on his bowling. Heis already thinking about the Champions Trophy because there is not much time between the end of the IPL and Champions Trophy. It is great tosee that the Indian players, who are looking forward to playing in theChampions Trophy or who will be in the scheme of things, are alreadyplanning and preparing for the big tournament,” he said.