Disneys classic 90s Aladdin and Lion King games are out Oct 29

first_img Preview • Nintendo Switch: All the latest details Video Games TV and Movies $289 26 Photos $299 2 Best Buy News • Are you a Nintendo Switch docker or hander? Amazon See It See It See It Mentioned Above Nintendo Switch (Gray) How To • How to transfer your Nintendo Switch account to a new Switch V2 With the Aladdin and The Lion King remakes each raking in more than $1 billion at the box office this year, it’s apparently time to remaster the ’90s video game adaptations of the originals. The two games, which will be packaged together as one release called Disney Classic Games: Aladdin and The Lion King, will come to the Nintendo Switch, Sony PS4, Microsoft Xbox One and PC on Oct. 29 for $30.Be prepare to face off against the hyenas in The Lion King. Disney The collection — developed by Nighthawk Interactive and Digital Eclipse — will also include the Sega Genesis and Nintendo Game Boy versions of Aladdin, along with something called the “final cut” and a trade show demo that hasn’t been available since 1993. Lion King will get Genesis, Nintendo SNES and Game Boy versions.center_img Review • Nintendo Switch review: Pure fun on a big-screen TV or on the go Share your voice Nintendo Switch $299 Walmart See it CNET may get a commission from retail offers. Nintendo Switch Lite: All colors, all angles, and vs. Switch $299 Comments Tags There’s no mention of an SNES version of Aladdin, which was significantly different from the Genesis one and was developed by Resident Evil creator Shinji Mikami. (We’ve embedded a comparison video of the SNES and Genesis versions.)The package will also include a world class menagerie of new features, like the ability to swap between upscaled and original graphics, visual filters, customizable controls, a rewind feature and Blu-ray-style extras.dcg-screenshot-6Stay one jump ahead of the lawmen in Aladdin. Disney The remaster was leaked Tuesday by Twitter user @wolverinefactor.First published Aug. 28 at 4:52 a.m. PT.Update, Aug. 29 at 9:30 a.m. PT: Adds release date and price. Disney Genesis Microsoft Sony Nintendolast_img read more

1 suspended as Ilias Kanchan passes airport security with gun

first_imgIlias Kanchan. File PhotoThe Civil Aviation Authority of Bangladesh (CAAB) on Wednesday suspended one of its officials for negligence of duty as film star Ilias Kanchan passed security check with a bag containing his revolver at Hazrat Shahjalal International Airport in Dhaka on Tuesday, reports UNB.CAAB chairman air vice marshal M Naim Hassan told UNB that they have been investigating into the incident and on-duty operator Fazlar Rahman was suspended over the issue.However, the former film star and an activist demanding road safety told this correspondent that the breach was “unintentional” and in the first scanning the gun was not detected while he was going to Chattogram from Dhaka.Meanwhile, Mohibul Haque, secretary to ministry of civil aviation and tourism, said that the revolver was spotted by the on-duty security officials during second scanning of Ilias Kanchan’s luggage.They immediately brought it to Kanchan’s notice and he admitted that he was carrying a licensed gun, he added.But the film star denied it saying, “During the second scanning after getting the boarding pass, suddenly I could recall that I had a gun in my bag and immediately I informed it to the security officer.”last_img read more

Department of Education Clears Fort Bend ISD After SixYear Probe into Disciplinary

first_imgiStock.com Listen 00:00 /06:14 Xcenter_img Share To embed this piece of audio in your site, please use this code: The Fort Bend Independent School District announced this week the U.S. Department of Education has completed a six-year investigation of the District’s disciplinary practices without findings of any wrongdoing.The Department of Education’s Office of Civil Rights (OCR) conducted the investigation. It focused on “whether the District discriminated against African-American students by disciplining them more frequently and harshly than other similarly situated students,” according to a news release from the District.“The OCR did not make any finding that the District discriminated against any students and did not otherwise identify any wrongdoing or non-compliance with federal law,” added the news release.Shelby Webb, a Houston Chronicle education reporter, told Houston Matters that Charles Dupre, the current superintendent, implemented measures on disciplinary practices when he joined the District in 2013.“His administration took several steps. One of the first was creating a Department of Student Affairs to address these issues, provide more teacher training when it comes to discipline practices,” said Webb.Dupre also put in practice restorative disciplinary practices. Webb noted that measure aims to provide students with more tools to “self-regulate their behavior, in terms of working out issues with their classmates.”Webb said Fort Bend ISD has had success with those measures given that the in-school suspension rate dropped from about 12 percent in the 2011-12 academic year to less than five percent in the 2016-17 academic year. Additionally, the out-of-school suspension rate fell from about eight percent to about 3.7 percent in the same time frame.Webb pointed out that, nonetheless, African American students are experiencing higher rates of in-school and out-of-school suspensions than their peers.“About eight percent of all black students in Fort Bend ISD were placed on out-of-school suspension in (academic year) 16-17 and that’s much higher when you compare them to Hispanic students about 3.2 percent of whom were placed on out-of-school suspension,” noted the reporter, who added that only about 1.6 percent of white students were placed on out-of-school suspension.The District said in its news release it will “continue to review and provide training regarding its discipline policies and procedures and will track and monitor discipline data.”last_img read more

Did You Know

first_img Did you know…?A student-athlete must be enrolled full-time to be eligible for practice, financial aid, and competition. If a student-athlete drops a class and becomes less than full-time, he or she is immediately ineligible for practice and competition. When adding a course to become full-time, the student is eligible for practice and competition once the course has been approved by the appropriate department head and submitted to the registrar. See Bylaw 14.2 below for more information. Print Friendly Version 14.2.2 Requirement for Competition. To be eligible for competition, a student-athlete shall be enrolled in at least a minimum full-time program of studies leading to a baccalaureate or equivalent degree, which shall not be less than 12 semester or quarter hours. (Revised: 6/1/07)14.2.2.1 Exceptions. The following exceptions to the minimum 12-semester or 12-quarter-hour enrollment requirement are permitted:14.2.2.1.1 Competition Prior to Initial Enrollment. A student-athlete may compete during the official vacation period immediately preceding initial enrollment, provided the student has been accepted by the institution for enrollment in a regular, full-time program of studies at the time of the individual’s initial participation; is no longer enrolled in the previous educational institution; and is eligible under all institutional and NCAA requirements. (See Bylaw 16.8.2.1.)14.2.2.1.2 Eligibility Between Terms. To be eligible for competition that takes place between terms (including competition between a student-athlete’s final term as an undergraduate student and first term as a graduate or post baccalaureate student), the student-athlete shall: (Revised: 1/11/89, 3/27/18)    (a) Have been registered for the required minimum full-time load (see Bylaw 14.2.2) at the conclusion of the term immediately preceding the date of competition, if the     student is continuing enrollment; or    (b) Be accepted for enrollment as a regular full-time student for the regular term immediately following if the student is either continuing enrollment or beginning enrollment     (see Bylaw 14.4.3.4).14.2.2.1.3 Final Semester/Quarter. A student-athlete may compete while enrolled in less than a minimum full-time program of studies, provided the student is enrolled in the final semester or quarter of the baccalaureate or graduate degree program and the institution certifies that the student is carrying (for credit) the courses necessary to complete degree requirements. Thereafter, the student shall forfeit eligibility in all sports, unless the student completes all degree requirements during that semester or quarter and is eligible to receive the baccalaureate diploma on the institution’s next degree-granting date. (Revised: 1/10/92, 1/16/93, 1/10/95, 2/1/05, 11/1/07 effective 8/1/08, 1/14/12, 8/21/12, 3/27/18)14.2.2.1.3.1 Eligibility Following Final Term. A student-athlete who is eligible to compete while enrolled less than full time during his or her final term remains eligible for regular-season competition that occurs after the term and any postseason event that begins within 60 days following the term. A student-athlete who attends a quarter-system institution and who graduates at the end of the winter quarter may compete in any postseason event (and preceding regular-season competition) that occurs during the same academic year following the completion of the winter quarter. (See Bylaw 12.8.) (Adopted: 4/29/04 effective 8/1/04, Revised: 3/27/18) Story Links 14.2 Full-Time Enrollment.14.2.1 Requirement for Practice. To be eligible to participate in organized practice sessions, a student-athlete shall be enrolled in a minimum full-time program of studies leading to a baccalaureate or equivalent degree as defined by the regulations of the certifying institution. (See Bylaw 12.8.2.5.) [D] (Revised: 1/10/92, 10/28/99,3/27/18)14.2.1.2 Drop/Add Course. A student-athlete no longer shall be considered enrolled in a minimum full-time program of studies (after dropping a course that places the student below full-time status) when the dropped course becomes official in accordance with procedures determined by the institution for all students. A student who is adding a course to reach full-time status shall become eligible for practice and competition once the course has been approved by the appropriate department head (or designated representative) and submitted to the registrar. (Adopted: 1/10/92)14.2.1.3 Exception—Final Semester/Quarter. A student-athlete with athletics eligibility remaining may participate in organized practice sessions while enrolled in less than a minimum full-time program of studies, provided the student is enrolled in the final semester or quarter of the baccalaureate or graduate degree program and the institution certifies that the student is carrying (for credit) the courses necessary to complete the degree requirements, as determined by the faculty of the institution. (Revised: 3/27/18)14.2.1.3.1 Eligibility Following Final Term. A student-athlete who is eligible for practice while enrolled less than full time during his or her final term remains eligible for practice during the remainder of the institution’s season, including postseason events. (See Bylaw 12.8.) (Adopted: 3/27/18)14.2.1.6 Exception—Practice During First Week of Class. A student-athlete may practice, but may not compete, during the institution’s first five days of classes if the student-athlete is enrolled in less than a minimum full-time program of studies, provided the student is otherwise eligible under all institutional, conference and NCAA requirements. (Adopted: 1/10/95 effective 8/1/95)last_img read more

RIUs top family resort in Punta Cana debuts brand new look

first_imgTags: Punta Cana, RIU Hotels & Resorts Travelweek Group PUNTA CANA — RIU Hotels & Resorts’ most family-friendly hotel in Punta Cana has reopened following a major overhaul to its rooms, restaurants, pools and services.ClubHotel Riu Bambu, inaugurated in 1999, was previously refurbished in 2004 and again in 2010, but only performed a complete overhaul earlier this year. The five-star, all-inclusive hotel now boasts new furniture and décor in all rooms, plus refurbished bathrooms, two new pools (in addition to three existing pools) with two new swim-up bars, and a new gymnasium next to the beach. The Riu4U club for young guests is another new item resulting from the refurbishment.Culinary options have also seen some changes. The hotel has seven restaurants including the new Spanish restaurant Olé and the gourmet eatery Kulinarium. Guests will continue to have the main restaurant available to them with international cuisine, as well as the Asian Hibachi, the Italian San Angelo, the Palm Beach steakhouse and the Mexican Mama Juana.More news:  Beep, beep! Transat hits the streets with Cubamania truckRIU Hotels currently has six hotels in Punta Cana: The Riu Palace Bavaro, Riu Palace Punta Cana, Riu Palace Macao, Riu Naiboa and ClubHotel Riu Bambu, which are located in the RIU complex. Clients also have free access to the Splash Water World water park, while the Riu Republica, the first adults-only hotel in the Riu Classic range, is located a mere two kilometres away. Riu Republica will showcase major changes at the end of this year, including 400 new rooms, four new restaurants, five bars and a new water park. Posted by << Previous PostNext Post >>center_img Wednesday, July 19, 2017 RIU’s top family resort in Punta Cana debuts brand new look Sharelast_img read more

Canadians visiting Maui are among Hawaiis big spenders Yes really

first_img Share Posted by Jean Sorensen Tuesday, March 6, 2018 Canadians visiting Maui are among Hawaii’s ‘big spenders’. Yes, reallycenter_img VANCOUVER — When the Maui Visitors and Convention Bureau (MVCB) landed in Vancouver recently to promote the tri-island destinations of Maui, Molokai, and Lanai, it should have been humming the show tune refrain “Hey Big Spender”.The latest figures from the Hawaii Tourism Authority (HTA), for January 2018, show that Canadians in Maui are among the big spenders for the destination, with their monthly increase in spending outstripping all other Hawaiian islands and resulting in a record expenditures to kick off 2018. The MVCB hosted a dinner at Vancouver’s Blue Water Café, eager to meet with the travel trade and keep the visitor numbers pumped.Leaning on research figures, Leanne Pletcher, Director of Media Relations and Marketing for the MVCB, said spend is definitely up. “The Canadian market has been very strong because of the weather,” she said. Figures for 2017 from the HTA show a 12% gain in Canadian visitors to Maui, the Hawaiian chain’s second largest island.HTA spending statistics for January 2018 show just how much all visitors are opening their wallets. All visitors to Maui, a long-time favourite destination for Canadians, increased their spending by a whopping 18% over last January, spending $548.5 million. That figure compares to the island of Hawaii (which saw a 1.8% gain to $268.2 million) and Kauai which had a 2.3% gain to $191.2 million.The January figures were the highest monthly totals ever recorded for each island, according to the HTA. Visitor spending on Oahu declined slightly (-1.9% to $662.0 million) in January compared to last year.Figures also show that the Canadian market is rebounding after a stagnant 2015 and 2016. In 2017, Canadian visitors spent $1.03 billion, an 8.1% increase over the previous year, while visitor arrivals increased 10.4% to 518,051. Scheduled air carrier seats out of Canada grew 5.5% in December 2017, with more seats out of Vancouver.The Maui delegation to Vancouver brought news of a number of new property renovations and excursions for travel agents.Krystle Alcain, PR Manager for Westin properties including Ka’anapali Ocean Resort and Nanea Ocean Villas, says the two properties cater to multi-generation family visits with one, two, and three bedrooms suites, with kitchen.WESTIN HOTELS & RESORTSWestin opened its Nanea Ocean Villas in April 2017, a resort property with eight buildings and 390 suites spread over 16 acres. Westin representative Krystle Alcain said the new resort offers one-, two- and three-bedroom suites and a highly sought-after property for multi-generational visits. “They have fully equipped kitchens,” she said, adding that there is also a dedicated children’s pool facility. The new property is also close to a Times Supermarket and has a small grocery outlet on site for essentials.More news:  Kory Sterling is TL Network Canada’s new Sales Manager CanadaThe Nanea is nearby the Westin’s other signature resort. Situated on 26 acres of beachfront, the Kaanapali Ocean Resort Villas is also a AAA Four Diamond resort that is suitable for multi-generational visits, said Alcain. One of the features of the two properties is the ability to share facilities. Westin’s third property on the Island is the Maui Resort and Spa, which unlike the villas, offers mainly hotel style rooms and is popular for couples, but can accommodate a couple with a child, says Alcain.THE RITZ-CARLTON KAPALUAThe Ritz-Carlton Kapalua is a property that has undergone a $30 million facelift with the bulk of the major revamp finished in January of this year. The luxury resort is a popular wedding site. “We have about 150 a year,” said Communications Manager, Deanna Miller, adding that several sites are allocated through the resort for weddings.The upgrade includes newly transformed guest rooms (with Nespresso coffee machines and wireless Internet able to accommodate 10 streaming devices), suites and residences, an enhanced lobby and pool and Kai Café. The decor reflects the heritage and scenic beauty of the island with rooms having floor to ceiling glass windows. The last phase of the upgrade will be the Banyan Tree and Terrace breakfast restaurants, which is to be complete in fall 2018.The renovations were started two years ago when Trinity Investment purchased the AAA Five Diamond resort which has 297 guest rooms and 107 residence condos (the first phase of the upgrade) from partnership Woodridge Capital and Colony Capital and others for $210 million. Trinity gained control of the 54 acre property in November 2016 and at that time announced it was embarking on an upgrade to make the 25-year-old facility more competitive.Candy Aluli, representing the Napili Kai Beach Resort, shows off one of Hawaii’s attractions: beautiful flora.NAPILI KAI BEACH RESORTCandy Aluli, representing Napili Kai Beach Resort, said the luxury property property will appeal to those interested in the environment. In December 2017 the Napili Resort embarked upon a campaign on its beachfront to educate bathers about the dangers of using sunscreen with ingredients that are harmful to the coral reefs. Guest checking in at the luxury property that is located in a reef protected bay will receive a free sample of a reef-safe sunscreen along with a discount coupon for purchasing more. The resort’s beach staff also walks the shoreline providing information to sunbathers on the beach about the importance of examining sunscreen ingredients. Research has found that sunscreen with harmful chemical toxins are killing the coral reefs in Hawaii.More news:  Flights cancelled as British Airways hit by computer problemThe 163-room hotel, located in a scenic bay, includes studios, one and two bedroom suites (most with kitchen) in 11 low-rise plantation style buildings. Approximately 96% of the rooms offer ocean views looking out over the bay it is situated in. Facilities include a beachfront restaurant and bar (the landmark Sea House Restaurant), four swimming pools, a boutique spa, fitness room, large ocean view whirlpool spa, and two 18-hole putting greens, one for adults and one for children.Golf and tennis are available in the adjacent Kapalua Resort community. The Napili Kai offers complimentary parking, free in-room wireless, kids age 10 and under eat free, no hidden charges or resort fees and other complimentary services.LANAI: HOME TO HAWAII’S MOST EXPENSIVE SUITEBridgett Parker, MVCB’s Social Marketing Manager, said those staying on Maui can easily travel to nearby Lanai by public ferry. While the 140-acre island is rustic in nature and 98% of it is owned by Oracle Corporation co-founder and billionaire Larry Ellison (who purchased the island in 2012), it does welcome visitors.Lanai also features Hawaii’s most expensive hotel suite, selling at $21,000 a night. Ellison acquired two hotels in the deal when he purchased the bulk of the island for $300 million. One features an 11-room Hawaiian style hotel, while the other is the Mandele Bay which went through an extensive upgrade to a luxury facility with Ellison overseeing the renovation. He reduced the number of rooms from 286 to 217 to provide more luxuries. Guests at the property gain access to the facility’s golf course which is a favourite of Bill Gates. Tags: Hawaii << Previous PostNext Post >>last_img read more

Free Up Your Summer Vietjet opens Nha Trang – Danang route

first_imgDa Nang‘Free Up Your Summer’ Vietjet opens Nha Trang – Danang routeCelebrating the year’s most attractive program “Free up your summer with Vietjet”, the airline has opened sales on its Nha Trang – Danang route to meet the traveling and trading demands of locals and tourists.The Nha Trang – Danang route will operate a return flight every day beginning 21 September 2018, with a flight time of approximately 1 hour per leg. The flight will depart from Nha Trang at 11:45 and arrive in Danang at 12:45. The return flight takes off at 13:20 in Danang and lands in Nha Trang at 14:20.To welcome the new route, Vietjet continues to offer the promotional series “Free up your summer with Vietjet” with millions of super saving tickets priced from only VND0 during the golden hours from 12:00 to 14:00 (GMT+7) from now until 31 July 2018.The promotional tickets are available on all sales channels during the golden hours from 12:00 to 14:00 (GMT+7) everyday on www.vietjetair.com (also compatible with smartphones at https://m.vietjetair.com) or www.facebook.com/vietjetvietnam (just click the “Booking” tab), hotline (+84)19001886, booking offices and agencies, both domestic and international. Payment can be easily made with debit and credit cards of Visa/ MasterCard/ AMEX/ JCB/ KCP/ any ATM card issued by 34 Vietnamese banks that have been registered with internet banking.Nha Trang and Danang – two famous coastal cities in central Vietnam are popular destinations for international and local tourists. With the new route, tourists will have more opportunities to discover these two interesting destinations with more flexible and easier timing.Aiming to be a “Consumer Airline”, Vietjet is continually opening new routes, adding more aircraft, investing in modern technology and offering more added-on products and services to serve all demands of customers. Vietjet is a pioneering airline that is loved by many for its exciting promotional and entertainment programs, especially during the festive season. With high-quality services, diverse ticket classes and special low-fare tickets, Vietjet offers itspassengers flying experiences on new aircraft with comfy seats, delicious hot meals, beautiful and friendly cabin crews, and other interesting added-on services.About Vietjet:Established in 2007, Vietjet is now leading the domestic aviation market in Vietnam and actively expanding its international flight network. After more than five years of operations, the airline has flown 40 million passengers, and been awarded 32 domestic and nine international accolades such as being named one of the Top 500 Brands in Asia 2016 and “The Best Asian Low Cost Carrier 2015” at the TTG Travel Awards 2015.Currently, the airline boasts a fleet of 60 aircraft, including A320s and A321s, and operates over 385 flights per day. It currently operates 93 routes in Vietnam and across the region to international destinations such as Hongkong, Singapore, Korea, Taiwan, China, Thailand, Indonesia, Myanmar, Malaysia and Cambodia. For more information, please visit its website at www.vietjetair.comSource = Vietjetlast_img read more

I still get the impression that there are forces b

first_imgI still get the impression that there are forces beneath the surface that spell big changes ahead.The gold price traded in a tight range throughout the Friday trading session everywhere on Planet Earth.  It appeared that every time gold tried to break above the $1,740 spot price mark, it got sold off…with the sell off at that London p.m. fix being the most obvious.The high tick of the day at the afternoon gold fix was $1,740.50 spot.  From there, gold got sold off…and closed for a small loss…down $1.10 on the day at $1,738.80 spot.  Net volume wasn’t overly heavy at 117,000 contracts.Silver traded sideways up until 10:00 a.m. in London…and then got sold down to its low of the day [around 32.05 spot] shortly after 1:00 p.m. GMT…about fifteen minutes before the Comex open.The subsequent rally got hit hard the moment that the London p.m. gold fix was in at 3:00 p.m. GMT…10:00 a.m. in New York…and then traded sideways into the 5:15 p.m. Eastern time electronic close.  The high tick at the fix was $32.89 spot.Silver finished the Friday session at $32.63 spot…up 32 cents on the day.  Net volume was pretty decent at 37,500 contracts…as I’m sure that JPMorgan et al were going short against all comers in that 2-hour early morning rally in New York, because it didn’t look like a short-covering rally to me.The dollar index opened at 80.81…and then traded lower…with the low tick [about 80.63] coming around 1:30 p.m. Hong Kong time.  From there it rallied until precisely 8:00 a.m. in New York, before trading mostly sideways for the remainder of the day.  The index closed just above the 81.00 mark at 81.05…up 24 basis points on the day.The dollar index and the gold price were in sync right up until 8:00 a.m. in New York…and then broke down entirely.Despite the fact that gold’s high tick came at 10:00 a.m. Eastern time, there was absolutely no sign of it in the share price action…as they were under selling pressure right from the 9:30 a.m. open of the equity markets in New York.  The HUI finished virtually on its low of the day…down 1.60%.Even though the silver price closed well into positive territory again, it didn’t help the shares too much…and Nick Laird’s Silver Sentiment Index closed down 1.09%.(Click on image to enlarge)The CME’s Daily Delivery Report showed that 4 gold and 8 silver contracts were posted for delivery on Tuesday.Over at GLD, an authorized participant withdrew 29,068 troy ounces of gold.  But SLV went in the other direction.  For the second day in a row, an authorized participant added a big chunk of silver.  This time it was 1,452,249 troy ounces.  On Wednesday it was 1,549,091 troy ounces of silver that was added, so a hair over 3 million ounces was added in those two day alone…and since last Friday [Nov. 2]…SLV has taken in almost 4.3 million ounces in total.  I’m sure Ted Butler will have something to say about this in his weekend commentary to his paying subscribers later today.Well, the good folks over at shortsqueeze.com finally updated their website with the latest short positions for SLV and GLD…but it was in the wee hours of this morning that it finally happened.  The short position in SLV declined by 9.24 percent…from 14,621,500 shares/ounces, down to 13,270,700 shares/ounces held short.  That’s still a lot of silver that’s owed to SLV…but don’t forget that 4.3 million ounces have been deposited in SLV since the beginning of the month, so this new short position number is probably wildly out of date by now.The GLD ETF went in the other direction, as the short position increased by 10.22 percent…from 16.99 million shares, to 18.73 million shares…or 1.87 million ounces in total.  That’s 58.16 tonnes of gold that should be on deposit at GLD, but isn’t.It was another big sales day at the U.S. Mint.  They reported selling 6,000 ounces of gold eagles…2,000 one-ounce 24K gold buffaloes…and 350,000 silver eagles.  Month-to-date the mint has sold 37,500 ounces of gold eagles…5,000 one-ounce 24K gold buffaloes…and 1,548,000 silver eagles.  Based on these sales, the silver/gold sales ratio is a bit over 36 to 1.  And as I keep saying…I do hope you’re getting your share, dear reader.The Comex-approved depositories showed that 935,196 troy ounces of silver were received by them on Thursday…and 554,126 troy ounces were shipped the door on the same day.  Of the amount received, JPMorgan Chase took in 785,407 troy ounces, bringing their depository total up to 25,030,654 troy ounces.  The link to that activity is here.Well, the Commitment of Traders Report showed improvements in the Commercial net short positions in both gold and silver…but certainly not as much as Ted Butler and I were expecting.In silver, the Commercial net short position declined by 4,054 contracts, or about 20.3 million ounces.  The Commercial net short position in silver is now down to 248.4 million ounces.The ‘Big 4’ traders are short 240.3 million ounces…virtually the entire amount of the Commercial net short position of 248.4 million ounces….and are also short a hair north of 45% of the entire Comex futures market in silver on a net basis.  The positions of the other 37 Commercial traders [the raptors] on the short side of the Comex silver market, are immaterial.Ted figures that JPMorgan Chase is still short a bit over 155 million ounces of silver on it’s own…and didn’t improve their position much during the reporting week, despite the big sell off on Friday, November 2nd.  Ted said that the raptors…some of the other 37 small traders [other than the ‘Big 4’] in the Commercial category…bought between 3,000-3,500 long contracts on that sell off.In gold, the Commercial net short position improved by 15,022 contracts, or 1.50 million ounces.  The Commercial net short position is now down to 20.77 million ounces of gold.The ‘Big 4’ short holders are short 13.10 million ounces of gold…and 31.9% of the Comex futures market in gold on a net basis.  The ‘5 through 8’ traders are short an additional 5.41 million ounces of gold.  So the ‘Big 8’ are short 18.51 million ounces of gold, or 45.0% of the entire Comex futures market in gold on a net basis…the same as silver.  The short positions of the other 39 other traders in the Commercial short category are immaterial.As you can see, the tail is wagging the dog in both silver and gold.Here are the ‘Big 4’ and ‘Big 8’ short positions show in “Days of World Production to Cover Short Positions“…Nick Laird’s most excellent graph that lays bare the price management scheme in all four precious metals for the world to see.  The silver short position is particularly egregious…as it always has been.(Click on image to enlarge)The Bank Participation Report for November also showed improvements in the short positions of both the U.S. and non-U.S. banks from the prior month.In silver, 4 U.S. banks are net short 35,252 Comex silver contracts.  Ted figures that JPMorgan holds a bit over 31,000 contracts of that amount all by itself…and I’m guessing that virtually all of the rest are unequally divided up between HSBC USA, Citigroup…and one other U.S. bank…in that order.The 15 non-U.S. banks are net short 14,286 Comex silver contracts…and I’d bet that between 70 and 80 percent of that amount is held by Scotia Mocatta…with the balance split up between the other 14 non-U.S. bank…whose individual positions would be immaterial.From the October report to the November report in silver, the 4 U.S. banks reduced their net short positions by only 2,532 Comex contracts.  The 15 non-U.S. banks reduced their collective net short positions by 2,826 Comex contracts.In gold, 5 U.S. banks are net short 98,101 Comex gold contracts, or 9.81 million ounces…a decline from 10.62 million ounces held short in October.The 21 non-U.S. banks are net short 59,436 Comex gold contracts, or 5.94 million ounces…a decline from  7.86 million ounces held short in October.As I mentioned in the Commitment of Traders report [from which the data for November’s Bank Participation Report is extracted]…the big 4 in silver…and big 8 in gold…are short 45% of each of their respective markets on a net basis.On a gross basis [before all market-neutral spread trades are subtracted] the Bank Participation Report shows that…15 banks are short 23.6% of the entire Comex palladium market…17 banks are net short 35.7% of the Comex platinum market…19 banks are net short 39.5% of the Comex silver market…and 24 banks are net short 38.4% of the entire Comex gold market.Once the spread trades from each market are subtracted from the total open interest…then the short positions, on a percentage basis, shoot sky high…another 5.5 percentage points in silver…and 6.6 percentage points in gold.  I’m sure platinum and palladium would be similar.This is precisely what Nick Laird’s graph above shows in all four precious metals…except its shown in days of world production to cover those short positions…but the ratios remain the same no matter in what unit of measure the graph is computed.I thank reader ‘David in California’ for providing this Reuters chart that requires no further explanation on my part.(Click on image to enlarge)This next chart is courtesy of reader Anthony D. Cattani…and it doesn’t require any further embellishment from me, either.(Click on image to enlarge)Since this is my Saturday column, here are all the stories that were still sitting in my in-box up until midnight last night.  I hope you can find the time to read the ones that interest you.Liberals seem to assume that if you don’t believe in their particular political solutions, then you don’t really care about the people that they claim to want to help. – Thomas SowellI have a couple of musical selections for you today…one a pop classic from the early 1970s…and the other one was a ‘classic’ from Billboard’s Top 10 in 1834.The tune from 1972 that was a big hit…and the only hit for British singer Daniel Boone…a.k.a. Peter Charles Green…and I remember playing it on radio station CHAR when I was in Alert, North West Territories.  If you can remember the words, feel free to sing along, because I’m sure you’ll remember the tune…and the link is here.Niccolò Paganini (1782–1840) encouraged Hector Berlioz (1803–1869) to write Harold en Italie. The two first met after a concert of Berlioz’s works conducted by Narcisse Girard on 22 December 1833, three years after the premiere of Berlioz’s Symphonie fantastique. Paganini had acquired a superb viola, a Stradivarius — “But I have no suitable music. Would you like to write a solo for viola? You are the only one I can trust for this task.”Berlioz began “by writing a solo for viola, but one which involved the orchestra in such a way as not to reduce the effectiveness of the orchestral contribution.” When Paganini saw the sketch of the allegro movement, with all the rests in the viola part, he told Berlioz it would not do, and that he expected to be playing continuously. They then parted, with Paganini disappointed.Harold in Italy was premiered on 23 November 1834 with the Orchestre de la Société des Concerts du Conservatoire, Chrétien Urhan playing the viola part, Narcisse Girard conducting.Paganini did not hear the work he had commissioned until 16 December 1838; then he was so overwhelmed by it that, following the performance, he dragged Berlioz onto the stage and there knelt and kissed his hand before a wildly cheering audience and applauding musicians. A few days later he sent Berlioz a letter of congratulations, enclosing a bank draft for 20,000 francs.The viola is a strange instrument…and some string players, notably violinists, look on it with thinly disguised contempt.  One first violinist with the Edmonton Symphony Orchestra told me the most famous of viola jokes…and it goes something like this… Q: What’s the difference between a viola and an onion? A: Nobody cries when you chop up a viola… But, having said that, this 4-moment symphony is a jewel…and it took me many listenings before I began to appreciate the work for what it is…and it would be certainly included in any ‘desert island’ collection I was putting together.This video recording is from 1976…and features the Orchestre National de France.  Donald McInnes is the soloist…and Leonard Bernstein conducts.  It’s posted over at the youtube.com Internet site…and the link is here.I wouldn’t read too much into yesterday’s price action, although it was obvious that JPMorgan Chase et al were standing by at the London p.m. gold fix to make sure that none of the four precious metals got out of hand to the upside once the ‘fix’ was in.Although I’m happy that we’re enjoying a bit of a rally since the big smack-down on November 2nd…I’m still not prepared to break out the party favours just yet.  The Commercial net short positions in both silver and gold in the Commitment of Traders Report, although better, are nowhere near a wildly bullish buy point…so I’m still on the look out for “in your ear”.But, having said all that, I still get the impression that there are forces beneath the surface that spell big changes ahead.  It’s just the timeline that I’m not certain about.  One thing that I would be happy to bet some money on is that by May 1, 2013 the price of both silver and gold will be substantially higher than they are at the moment…as JPMorgan Chase et al can’t keep this up forever.  How fast we get there and how high we go, will very much depend on whether the bullion banks are still in control of the price as these expected rallies get underway.Will they be short covering rallies…or will the powers-that-be just stand aside for a little while and let the prices rise in sort a controlled retreat fashion…which is the process they’ve been using since 1999.  I don’t know the answer to that…and only time will tell.But I’m still ‘all in’.See you on Tuesday. Sponsor Advertisement On October 30, 2012, Mason Graphite Inc. began trading on the TSX Venture Exchange under the symbol “LLG”. Mason Graphite is focused on the exploration and development of its Lac Guéret graphite property located in northeastern Quebec. Based on the current National Instrument 43-101 compliant Measured & Indicated mineral resource of approximately 7.6 million tonnes grading 20.4% Cgr (carbon as graphite), the Lac Guéret property hosts one of the highest grade graphite deposits known in the world. Mason Graphite is led by Benoit Gascon, CA CMA, who has held 20 years of executive positions at Timcal, including over 6 years as CEO. Timcal, now owned by Imerys, is one of the largest graphite producers in the world. Mason Graphite has 56.9M shares outstanding and 74M shares on a fully diluted basis. For more information on the company, please visit our website, email info@masongraphite.com or call +1 (416) 861-1685.last_img read more

I see you standing here asking for help about on

first_imgI see you standing here, asking for help, about once a week. You are always polite, and I respect that. I’d like to do something for you… something that would matter long-term. Giving you a few notes or coins now and then may be fine, but I’d really like to improve your situation more permanently. In other words, I’d like to give you a job. I used to hire people, and I especially liked hiring people who had been denied breaks. I did that whenever I could. If you and I could be transported back in time, I’d hire you. And I’d feel good about it, because I think having a job would do you a lot of good. That fact is, however, that I can’t hire you, and I’d like you to know why. I used to run my own contracting firm. I enjoyed the work and I liked being able to drive past a building and say, “I made that.” Having employees, however, was torture. I liked having them in some ways, of course – I liked the guys and it made me happy to see them take care of their families with paychecks that I signed. That was very gratifying. But it wasn’t enough, and there are three reasons why: #1: Making Payroll My first problem was simply cash flow. I was solely responsible for having enough money in the bank every week, and that could be nerve-wracking, especially when customers weren’t paying their bills on time. It’s not fun to think that a family won’t be able to buy groceries if you can’t collect your invoices. Still, that part didn’t cause me to give up on employees. It was hard, but so long as my employees were working, we were making money, so there was always something coming in at some point. Somehow, I was able to pull it off. #2: Being Hated Over time, some of my employees became jerks. This seemed to grow from envy and from stupid ideas about labor versus management. These guys decided that I was getting rich off of them, and demanded I pay them more – more than they deserved and more than the company could afford. And the really nasty part was this: It was always the guys I had done the most for who hated me most. And as soon as I sat down with them and explained why I couldn’t pay them more, they started stealing from me. I fired the thieves, of course, but these experiences really soured me on employees. I had not only given these guys a job, but I had legitimately felt good about helping to feed their families. In return, they hated me, called me names, and stole from me. By itself, that was almost enough to make me swear off employing people, but not quite. #3: The IRS What really drove me over the edge was dealing with the government and the IRS in particular. They were abominable. I had to file forms with every payroll, and if anything on them was wrong, they penalized me – heavily. And if I paid them a single day late, they penalized me – heavily. And if they said I did something wrong – even if I didn’t – there was no way to change their verdict. Reason and evidence simply didn’t matter. I eventually talked to a tax lawyer who explained the situation to me. He said: Forget about fighting, Paul. There is no ‘innocent until proven guilty’ in tax court. You’re automatically guilty, and you have to try to prove yourself innocent… which is very hard and very expensive. Just pay them. I know you hate that, but you have no other choice. Fighting them would ruin you. It wasn’t just the money that got me about this – it was that they were nasty, arrogant, heartless tyrants. Having the facts on my side didn’t matter. Intelligent arguments didn’t matter. Either I paid what they demanded or they would hurt me worse. In many ways, it wasn’t much different than the local gang of street thugs demanding protection money. So, that’s why I can’t hire you: Having employees locked me into a single role in life, that of a despised slave. When I finally realized that, I walked away. I was lucky that I had the ability to move into specialties and to thrive in difficult niches; other guys probably couldn’t have. So… What I really want you to know is this: I’d like to help you. You deserve a chance at a decent job. I’d like to be the guy who gave it to you, but the system demands that I must live as a slave in order to do so. And I won’t do that. I very much wish that things were different, and I feel sorry every time I drive by that I can’t hire you. But I would never ask anyone to live as a slave, and I won’t live that way myself. I wish you well, and if life in these parts should ever pull back from the present reign of oppression, I hope to run into you. And on that day, I hope to either hire you or do business with you. We would both have much to gain from it. Paul Rosenberg FreemansPerspective.comlast_img read more

Theres new evidence that mild pulses of electrici

first_imgThere’s new evidence that mild pulses of electricity can relieve depression — if they reach the right target in the brain.A study of 25 people with epilepsy found that those who had symptoms of depression felt better almost immediately when doctors electrically stimulated an area of the brain just above the eyes, a team reported Thursday in the journal Current Biology. These people were in the hospital awaiting surgery and had wires inserted into their brains to help doctors locate the source of their seizures.Several of the patients talked about the change they felt when the stimulation of the lateral orbitofrontal cortex began, says Kristin Sellers, an author of the paper and a postdoctoral researcher at the University of California, San Francisco. One person’s response was: “Wow, I feel a lot better. … What did you guys do?” The stimulation only lasted a few minutes. After it stopped, the effect on mood quickly faded. To be sure that the effect was real, the researchers also pretended to stimulate the lateral OFC in the same patients without actually running current through the tiny wires implanted in their brains. In those sham treatments, there was no discernible change.The results add to the evidence that patients with depression can be helped with an approach known as deep brain stimulation.DBS is an approved treatment for tremors, including those associated with Parkinson’s disease. But results with depression have been less consistent, and DBS isn’t approved for this purpose by the Food and Drug Administration.The latest study represents “another piece in a very complicated puzzle, a very important piece,” says Dr. Helen Mayberg, a pioneer in the use of DBS to treat depression. The study also offers strong evidence that stimulating the OFC can temporarily improve the mood of a person who is feeling depressed, says Mayberg, who directs the Center for Advanced Circuit Therapeutics, which is part of the Mount Sinai Health System in New York. But it’s unclear whether the stimulation can produce long-lasting changes, she says. Also, the study couldn’t answer a critical question because it only looked at people who were reporting transient symptoms of depression. “What happens if you did this in people who actually have failed every kind of treatment for a major depressive episode and are chronically and intractably ill,” Mayberg says.Meanwhile, her own team has been able to help about 80 percent of those patients by stimulating a different area of the brain — one that happens to share many connections with the OFC. The latest study offers “more evidence that [DBS] is something that is real and will work for depression,” says Al Fenoy, an associate professor of neurosurgery at the University of Texas Health Science Center at Houston.Fenoy is part of a team that has had success treating depression by stimulating yet another brain area that shares connections with the OFC. “We’re all (working) along a very similar pathway,” he says. “One of the common denominators might be this orbitofrontal area.”But it’s also possible that different types of depression will require different targets, Fenoy says.All of the research on brain stimulation reflects a move away from the long-held view that depression is caused by a chemical imbalance in the brain. “A more sort of modern conception is thinking of depression as a circuit dysfunction, meaning that there’s something about the way cells in the brain are talking to each other that is not quite right,” says Dr. Vikram Rao, an author of the new study and an assistant professor of clinical neurology at UCSF.So researchers have been trying to identify faulty circuits and make them work better using electrical pulses. The challenge has been to find areas that have a really good connection to the malfunctioning circuit”The way that I like to think about it is we’re trying to get onto a highway and there’s a lot of different on-ramps,” Sellers says.The UCSF team took a novel approach to this task by studying patients with epilepsy who were awaiting surgery. That meant they already had wires inserted into their brains to help doctors locate the source of their seizures.In a previous, related study, UCSF researchers had used a different group of epilepsy patients to identify circuits in the brain that indicated whether people were happy or sad. This time, they were able to use these wires to not only monitor various brain circuits involved in mood but also electrically stimulate some of those areas.The researchers were able to use the technique in many different areas in the brain. And Sellers says they got an immediate response when they stimulated the OFC. “What we found was that consistently, stimulation in the lateral OFC was improving mood in symptomatic patients,” Sellers says. What’s more, more powerful stimulation produced a more dramatic improvement in mood, she says. There were no issues with side effects, including mania, which has been seen in some previous experiments with brain stimulation.That’s probably because the OFC offers a really good on-ramp to brain networks involved in depression, Rao says. “It does seem to be a crossroads for connecting many different brain regions that had been implicated in regulating our mood.”And Rao says the results suggest that stimulation of this area is improving the function of a faulty circuit, rather than just making everyone happier.”Only the people who had symptoms [of depression] to start with improved their mood, which suggests that perhaps the effect of what we’re doing is to normalize activity that starts off abnormal,” Rao says. Copyright 2018 NPR. To see more, visit https://www.npr.org.last_img read more

Bloomberg Opens 75 Million Venture Capital Fund

first_img Next Article Opinions expressed by Entrepreneur contributors are their own. Learn how to successfully navigate family business dynamics and build businesses that excel. June 5, 2013 Add to Queue –shares Image credit: qz.com Technologycenter_img Bloomberg L.P. announced today the creation of a $75 million venture capital fund called Bloomberg Beta. It says it will be run strictly for financial return rather than as a means of bringing new products and services to Bloomberg.The fund’s focus, says Roy Bahat, the head of Bloomberg Beta, is on “the next horizon for Bloomberg” in areas such as data technology, media distribution and human-computer interactions. As startups continue to disrupt established markets, many large companies are creating investment arms and incubator programs to pursue innovation.Bloomberg quietly established the fund in January, with headquarters in San Francisco, and it has already made investments in a handful of startups. Among them are cloud-computing provider Nodejitsu and programming-tutorial site Codeacademy.Bloomberg Beta exists as a separate legal entity from its parent company. Bahat says this structure will prevent ethical breaches such as preferential coverage of the startups in its portfolio by reporters in Bloomberg’s news division.Ian Finley, a vice president of research at Gartner, a technology research firm, disagrees. “The legal entity thing doesn’t actually change the picture,” he says. A “side benefit” of Bloomberg Beta may be that it can provide Bloomberg News and Businessweek reporters with “some visibility into reporting areas that their competitors might not have,” says Finley. Bloomberg came under fire last month over news that its reporters routinely spied on the activity of people who were using the company’s Bloomberg Terminals, a computer system used widely in the financial industry.Finley doesn’t doubt that Bloomberg journalists are forbidden from showing favoritism to startups in which Bloomberg Beta actually invests. But he says that won’t necessarily stop the venture capitalists from passing tips to reporters about other startups they have examined. “A typical VC firm of $75 million is not going to make that many investments, but they will review thousands of startups a year,” he says. “So there may be a huge amount of value there, with a very low chance for ethics problems.”But Bahat says his firm won’t provide inside information to the parent company’s news division. “The way that I’ll work with Bloomberg journalists is exactly the same way that I would work with journalists anywhere else,” he says. “I will protect the confidentiality of the companies that we invest in, and of the companies that we don’t invest in.”For a company with a current market capitalization of $1.25 billion, $75 million may seem like a small bank account for a venture fund. But Bahat says it’s “just the right amount of money” for working with early-stage companies. “A fund of this size actually enables you to do a lot,” he says. “We’ll be writing checks at a range of different sizes.”Bloomberg is not the only big media company to cultivate startups. The New York Times Co. also invests in digital startups. What’s more, the Times Co. opened an incubator earlier this year for early-stage media companies. Its inaugural class of three is halfway through the four-month program.”The Times has some of the smartest people in the industry, working on some of the same problems that we are,” says Andrew Whalen, co-founder of Delve, one of the timeSpace startups. Delve is a social news reader and recommendation engine designed to keep organizations on top of crucial news in their industry. “Having access to the knowledge inside this company has been pretty incredible.”Related: The New York Times Gets Into the Incubator GameWhalen calls his tenure so far at timeSpace a mutual learning experience, in which he and his seven coworkers met with “a good cross-section of teams at the Times, everyone from design to product to tech to the newsroom.” Times staffers have provided crucial insight and feedback as Delve redesigns its product, Whalen says.Whalen would not confirm whether or not the Times Co. is interested in investing in Delve. But he did say his eight-person startup will be launching a private beta with pilot companies this summer, and is planning to do a “broader public push” in the fall, at which time the company will seek Series A financing.Bloomberg Beta and other recent efforts by large media companies to cultivate startups have a predecessor in IDG Ventures, the venture-capital arm of International Data Group, the American company that owns the PCWorld and Macworld media properties. The company launched IDG Ventures in 1996.Why is now the right time for a Bloomberg venture-capital fund? Bahat cites the falling cost of starting a company, which gives rise to exciting investment opportunities for large companies. “Sometimes the best inventions come from outside your walls, and you have to embrace that,” Bahat says. Free Webinar | July 31: Secrets to Running a Successful Family Business Brian Patrick Eha 5 min read Bloomberg Opens $75 Million Venture Capital Fund Register Now »last_img read more

Get Ready for the Achocolypse The World Is Running Out of Chocolate

first_img Reporter Add to Queue –shares Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Chocolate Kate Taylor Dark Chocolate Today in horrifying news: the world is running out of chocolate.Chocolate makers Mars and Barry Callebaut are anticipating chocolate shortages in coming years, reports The Washington Post. The industry already can’t keep up with how much chocolate the world wants to eat – and it’s only going to get worse.Last year, the demand for chocolate was roughly 70,000 metric tons more cocoa than produced – a difference the industry expects to widen. In fact, by 2020, Mars and Barry Callebaut predict that we will want 1 million more metric tons of chocolate than the industry will be able to churn out. By 2030, the figure could swell to 2 million metric tons, the paper reports.Why can’t chocolate makers keep up the cocoa-hungry customers? Crops of cocoa have been suffering due to dry weather in West Africa, where most cocoa is produced, and a fungal disease that has wiped out around a third of global coca production. The problems are similar to the coffee industry, where a fungus threatens to drag down the global production of coffee by as much as 40 percent.Related: What the Devastating Coffee Fungus Means for U.S. Coffee ShopsIncreased demand has also played a role in potential shortages. With chocolate consumption increasing in countries like India and China, demand for cocoa beans in Asia has risen 29 percent over the last five years. Plus, the Washington Post says the rising popularity of dark chocolate means more cocoa is used per serving than ever before in the era of the milk chocolate bar.The long-term future of chocolate looks even more treacherous. The chocolate industry relies primarily on small farms with increasingly elderly farmers and disease-prone aged trees. If the next generation wants to enjoy chocolate, a new generation of farmers is going to have to step up.Already, chocolate makers are raising their prices. Hershey announced a price hike for the first time in three years in July, and the candy company’s competitor Mars followed suit soon after. Related: Hershey Raises Prices for First Time in 3 Years as Cocoa Costs Spike November 17, 2014 Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. 2 min read Image credit: Pixabay Next Article Get Ready for the ‘Achocolypse’: The World Is Running Out of Chocolate Enroll Now for $5last_img read more

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

first_imgIn our previous study, what we did was to develop CRMP2 knock-in mice and genetically inhibit its CRMP2 phosphorylation. As a result, the CRMP2 knock-in mice showed promotion of axonal regeneration after a spinal cord injury. From this, we hypothesized that the same phenomenon could also be observed after optic nerve injury.”Professor Toshio Ohshima, Waseda University Source:Waseda UniversityJournal reference:Kondo, S. et al. (2019) Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury. Scientific Reports. doi.org/10.1038/s41598-019-43658-w. The findings of this study, recently published online in Scientific Reports, could be translated into the development of novel treatments for patients with optic neuropathies, such as traumatic injury and glaucoma.When diagnosed with glaucoma, blind spots develop in the visual field and could lead to blindness as the optic nerve deteriorates. Such deterioration and loss of function of nerve fibers, or axonal degeneration, also occur in traumatic nerve injury and neurological diseases, such as Alzheimer’s disease and ALS. Currently, methods for completely repairing the retina, spinal cord, and other parts of the central nervous system after injury or degeneration do not exist because axonal regeneration is restricted by inhibitory factors.In past studies, potential mechanisms which inhibit axonal regeneration have been found, and addressing these mechanisms were thought to bring scientists a step closer in developing new therapeutics for damages to the central nervous system.The CRMP2 protein molecule functions to stabilize microtubules, which provide structural support for the central nervous system at the neuronal cellular level and promote polymerization by binding to tubulin dimers. However, these functions are prevented by various kinases through phosphorylation, a mechanism regulating neuronal proteins. Our experimental data indicate that inhibition of CRMP2 phosphorylation will be a novel approach to the development of treatments for human optic nerve injuries, but further study will be necessary for practical application.For instance, some studies suggest that CRMP2 phosphorylation plays a role in forming myelin, an important substance for sufficient functional recovery of regenerated axons. Additional treatment to facilitate myelination will be required to realize functional recovery after optic nerve injury.”Professor Toshio Ohshima, Waseda Universitycenter_img Related StoriesUsing NMR to Study Protein Structure, Dynamics and MechanismsHinge-like protein may unlock new pathways for cystic fibrosis treatmentSorting protein in neurons protects against neurodegenerative disordersTo investigate, the scientists compared the degeneration and regeneration of the optic nerve between wildtype and CRMP2 knock-in mice after an optic nerve injury introduced by an optic nerve crush, a procedure in which the left optic nerve was exposed and crushed for 5 seconds with a tweezer at a site approximately 1mm behind the eye’s globe. They found that destabilization and depolymerization of microtubules after an optic nerve crush injury was suppressed in CRMP2 knock-in mice, and the loss of retinal ganglion cells, the projection neuron of the eye, was also reduced.The research team also observed that the protein level of GAP43, a molecular marker for axonal regeneration, was higher in the optic nerve from CRMP2 knock-in mice than that from wildtype mice 4 weeks after the optic nerve crush. Additionally, the number of axons increased in the optic nerve after the optic nerve crush in CRMP2 knock-in mice. Reviewed by James Ives, M.Psych. (Editor)May 22 2019A new study by Professor Toshio Ohshima of Waseda University has found that the inhibition of phosphorylation of collapsing response mediator protein 2 (CRMP2), a microtubule-binding protein, suppresses degeneration of nerve fibers and promotes its regeneration after optic nerve injury.last_img read more

Slovakia to feel most pain from Trump car tariffs experts

first_img Citation: Slovakia to feel most pain from Trump car tariffs: experts (2018, July 1) retrieved 18 July 2019 from https://phys.org/news/2018-07-slovakia-pain-trump-car-tariffs.html As the world’s largest per capita car producer, Slovakia stands to be hit hardest if US President Donald Trump makes good on his threat to impose a 20 percent tariff on cars imported from the EU, analysts say. Trump’s threat was the latest salvo in an escalating trade war that saw the European Union slap duties on US-made jeans and motorcycles in a tit-for-tat response to US tariffs on European steel and aluminium exports.The spectre of US tariffs that sent shares in Fiat Chrysler, Daimler and BMW tumbling on European stock exchanges also spooked Slovakia’s automotive sector.It boasts Germany’s Volkswagen—which is Slovakia’s biggest private-sector employer—France’s PSA and South Korean Kia along with more than 300 automotive supply companies.All told, they generate over 300,000 jobs in the eurozone country of 5.4 million. Jaguar Land Rover will also open a new plant in September. This makes Slovakia the EU’s leading car and car part exporter to the United States in terms of share of GDP—and the most vulnerable to tariffs.”The ratio of overseas car exports to Slovakia’s GDP is significantly the highest among all countries of the EU, with it being up to 1.7 percent,” the Slovak Institute for Financial Policy (IFP) said in a study.”An increase in customs duties on car imports would have the biggest impact on Slovakia,” it concluded. As the only Slovakia-based carmaker that exports directly to the US, Volkswagen—and its many local suppliers—will suffer the most should US tariffs be slapped on the high-end Touareg, Audi Q7 and Porsche Cayenne models produced at its Bratislava plant.Overall, the carmaking sector has a 44 percent share of Slovakia’s total industrial production and 35 percent of its exports.Last year, 1,001,520 cars rolled off assembly lines in Slovakia and exports were worth 3.7 billion euros ($4.3 billion). Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 AFP Germany’s Volkswagen exports cars from Slovakia to the US US tariffs on car imports are a double-edged sword Per capita, no country produces more cars than Slovakia Slovak Economy Minister Peter Ziga has said that Bratislava would rally for unity across the European Union in the interests of keeping the car sector tariff-free.Carmakers based in Slovakia have so far declined to comment on possible US tariffs.”As these plans are only speculations, we will not comment on them,” Volkswagen Slovakia spokesman Michal Ambrovic told AFP.The German company’s Slovak operation produced 361,776 cars last year, and 99.7 percent of its production was exported, with 20 percent to the US, according to an internal report made available to AFP.Groupe PSA Slovakia, maker of Citroën C3 and Peugeot 208 in Trnava, also declined to comment on the tariff impact, but spokesman Peter Svec did say that its plant does not sell to the US market. PSA produced 335,296 cars in 2017, 91 percent of its production was sold to customers EU countries, according to the company annual report.KIA Slovakia spokesman Andrej Sahaj also confirmed that sales of its vehicles are restricted to Europe. Annual production has exceeded one million cars in each of the last three years and is forecast to grow by more than a third by 2020.’Challenge’A 25 percent tariff on cars could cost Slovakia approximately 90 million euros, according to IFP calculations.Tariffs would “definitely pose a challenge for Slovak carmakers reaching out to customers in the United States,” Jan Pribula, Secretary General of the Automotive Industry Association of the Slovak Republic (ZAP), told AFP.last_img read more

Is NCPs Sharad Pawar eyeing a bigger role at the CentreIs NCPs

first_imgFile Photo of NCP leader Sharad Pawar.   –  PTI SHARE Published on COMMENT After backing Mamata Banerjee, Chandrababu Naidu and Mayawati as top contenders for the prime ministerial post in case any single party or an alliance fails to secure majority, Nationalist Congress Party (NCP) chief Sharad Pawar said he is not in the race for the top post but at the same time has made it clear he will play a vital role in bringing all leaders together. As the fourth and last phase of polling ended in the State on Monday, Pawar told media that even if his party wins all 22 seats it contested in Maharashtra, it was unrealistic for him to join the race for the top post. However, he said he was going to ensure that non-BJP leaders come together to stop the BJP regaining power.NCP insiders said Pawar was in constant discussions with various non-BJP and non-Congress leaders, including Mamata Banerjee and Chandrababu Naidu. Despite Pawar refusing his contest for PM’s post, many NCP candidates have appealed voters that NCP should win maximum seats to facilitate Pawar’s claim on the post. A history with BJPEven as the NCP and the Congress have fought Lok Sabha elections together in Maharashtra, the State Congress leaders are wary of Pawar’s moves as he had announced unconditional support to the BJP in Maharashtra after 2014 Assembly polls. The BJP had emerged as a single largest party and Shiv Sena had not made up its mind to support the BJP to form the government. Pawar had then announced support to the BJP even as the BJP leaders had not asked for it. Finally, Sena joined the government and NCP had to sit in the opposition in the State Assembly. Prime Minister Narendra Modi shares cordial relations with Pawar and had praised the NCP president as an “example” to others in public life. “I have personal respect for Sharadrao. I was Gujarat Chief Minister. He helped me walk by holding my finger. I feel proud to pronounce this publicly,” Modi had stated earlier. During his election campaign in Maharashtra PM Modi castigated Pawar but at the same time questioned on how a leader like Pawar’s stature be with the Congress. Pawar during the election campaign had insisted that he has no plans of retiring from politics and has a long way to go. After addressing about 80 rallies across the State , the 79-year-old veteran is on tour to drought-affected areas in Maharashtra. Pawar was in drought affected Solapur immediately after casting his vote in Mumbai on Monday. April 30, 2019 politics state politics COMMENTS SHARE SHARE EMAIL national electionslast_img read more

New cabinet ministers to be sworn in at 3 pm Saturday Goa

first_imgNew cabinet ministers to be sworn in at 3 pm Saturday: Goa CM Pramod SawantGoa Chief Minister Pramod Sawant refused to name the MLAs who would be inducted but said all the four would be from the Bharatiya Janata Party, with three of them from the legislators who joined the party on Wednesday.advertisement Press Trust of India PanajiJuly 13, 2019UPDATED: July 13, 2019 04:58 IST Goa Chief Minister Pramod Sawant said the swearing-in ceremony would be held at 3 pm Saturday. (Photo: PTI)Goa Chief Minister Pramod Sawant said late on Friday night that he would reshuffle the cabinet on Saturday replacing four ministers and the swearing-in ceremony would be held at 3 pm.Ten Congress MLAs had on Wednesday joined the Bharatiya Janata Party (BJP) increasing the strength of the party to 27 on the floor of the House.Pramod Sawant said the three members from a coalition partner, Goa Forward Party, and an Independent MLA Rohan Khaunte would be dropped from the cabinet.Pramod Sawant refused to name the MLAs who would be inducted but said all the four would be from the BJP, with three of them from the legislators who joined the party on Wednesday.Speculations are rife that former leader of opposition Chandrakant Kavlekar, Philip Nery Rodrigues and Atanasio Monserratte would be inducted in the cabinet along with Deputy Speaker Michael Lobo.Pramod Sawant said the swearing-in ceremony would be held at 3 pm Saturday.This would the second cabinet reshuffle by Pramod Sawant since he took over as the chief minister three months ago. In his first cabinet reshuffle, Sawant had inducted MGP’s breakaway MLA Deepak Pauskar after dropping then deputy chief minister Sudin Dhavalikar.Asked why allies are being dropped from the cabinet, the chief minister said the decision has been taken as per directives of the central leadership.”I don’t want to go into details. We have taken this decision to give good governance to the people,” he said.Sawant has the support by three MLAs from the Goa Forward Party and an Independent.Goa Forward Party (GFP) chief and Deputy Chief Minister Vijai Sardesai had during the day said they are hoping for an amicable solution to the crisis.”The GFP is a part of the NDA and had joined the BJP-led government after talks with the saffron party’s national leadership,” Sardesai said, adding, “The present state BJP leaders were not part of the discussions then. As such, we will take appropriate steps only after talking to NDA leadership at the Centre.””We have not yet received any official communication from the BJP leaders. On the contrary, we have received indications that the matter will be sorted out amicably,” he said.Ten of the 15 Congress MLAs, led by the leader of Opposition, Chandrakant Kavlekar, switched sides and joined the Bharatiya Janata Party (BJP) on Wednesday.While the 10 MLAs and Lobo returned from Delhi, Sawant stayed back to attend a high-level meeting on Friday evening on the issue of mining in Goa, which has come to a standstill following a February 2018 Supreme Court order.Also Read | Goa CM Pramod Sawant seeks resignation of 3 ministers, independent MLA to induct new facesAlso Watch | Leaderless Congress headed towards self-destruction?For the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byAkriti Anand Nextlast_img read more

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New Delhi:? AFP Section 7 makes dignity conditional First, enabling it to limit citizen rights. You do that with color, For all the beauty of the embroidery and the armor. read more